Does Ozempic Cause Diarrhea?

Ozempic slows down gastric emptying, meaning your food stays in your stomach longer. This means your digestive system has to work hard to adjust, which may lead to diarrhea.

You’re most likely to experience gastrointestinal side effects like diarrhea, nausea, and vomiting when you first start the medication or when you increase your dose. Once your body adjusts, the diarrhea will likely improve.

The biggest danger with diarrhea is dehydration, which happens when your body loses too much water and salt. To manage diarrhea, try this:

• Drink fluids: Sip water, salty soups, or other clear fluids throughout the day. You can also use oral rehydration solutions available in most pharmacies.
• Watch your diet: You can eat normally, but try to avoid dairy, alcohol, and spicy food until your stomach settles. Some people prefer eating starchy, light foods, like white rice, crackers, or pasta in the early stages of diarrhea.
• Talk to a professional: If your diarrhea is severe, doesn’t go away, or you notice signs of dehydration, like dark-colored urine, contact a healthcare professional. Severe fluid loss can sometimes lead to kidney problems.

The best way to prevent diarrhea with Ozempic is to follow the dosage escalation schedule your doctor recommends. You typically start with a low dose of 0.25 milligrams (mg) for 4 weeks before moving up to a higher dose. This gradual increase is designed to help your body get used to the medication and reduce the risk of stomach issues.

Taking your medication on the same day every week will also help to keep the levels of medication in your body steady.

If you’re concerned that your diarrhea is lasting too long or it’s interfering with daily life, ask a doctor or pharmacist for advice.